K411E (p.Lys411Glu) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
K411E (p.Lys411Glu) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
K411E (p.Lys411Glu) variant details
- p.Lys411Glu
- rs1253864619
- gnomAD 6-111572936-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.35
- REVEL 0.14
- CADD 24.80
- PolyPhen-2 0.96
- SIFT 0.09
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available