I453V (p.Ile453Val) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
I453V (p.Ile453Val) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
I453V (p.Ile453Val) variant details
- p.Ile453Val
- gnomAD 6-111566545-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.34
- REVEL 0.24
- CADD 24.60
- PolyPhen-2 0.99
- SIFT 0.08
- Population evidence available
- Structural context available
- Literature evidence available