I453F (p.Ile453Phe) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
I453F (p.Ile453Phe) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data, published literature, and structural context.
I453F (p.Ile453Phe) variant details
- p.Ile453Phe
- gnomAD 6-111566545-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.51
- CADD 29.00
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available