I442T (p.Ile442Thr) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
I442T (p.Ile442Thr) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
I442T (p.Ile442Thr) variant details
- p.Ile442Thr
- rs1197932494
- gnomAD 6-111567655-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.304
- REVEL 0.09
- CADD 23.60
- PolyPhen-2 0.08
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available