I440V (p.Ile440Val) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
I440V (p.Ile440Val) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
I440V (p.Ile440Val) variant details
- p.Ile440Val
- gnomAD 6-111567671-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.07
- CADD 17.40
- PolyPhen-2 0.01
- SIFT 0.80
- Population evidence available
- Structural context available
- Literature evidence available