I440T (p.Ile440Thr) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
I440T (p.Ile440Thr) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
I440T (p.Ile440Thr) variant details
- p.Ile440Thr
- gnomAD 6-111567685-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.489
- REVEL 0.37
- CADD 27.00
- PolyPhen-2 0.99
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available