G435S (p.Gly435Ser) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
G435S (p.Gly435Ser) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.69 / 1. The record also includes population frequency data, published literature, and structural context.
G435S (p.Gly435Ser) variant details
- p.Gly435Ser
- rs1315991109
- gnomAD 6-111572909-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.686
- REVEL 0.65
- CADD 31.00
- PolyPhen-2 1.00
- SIFT 0.03
- Population evidence available
- Structural context available
- Literature evidence available