F427L (p.Phe427Leu) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
F427L (p.Phe427Leu) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data, published literature, and structural context.
F427L (p.Phe427Leu) variant details
- p.Phe427Leu
- gnomAD 6-111572924-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.20
- CADD 24.60
- PolyPhen-2 0.75
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available