E408G (p.Glu408Gly) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
E408G (p.Glu408Gly) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data, published literature, and structural context.
E408G (p.Glu408Gly) variant details
- p.Glu408Gly
- gnomAD 6-111572944-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.581
- REVEL 0.49
- CADD 33.00
- PolyPhen-2 0.93
- SIFT 0.04
- Population evidence available
- Structural context available
- Literature evidence available