D451N (p.Asp451Asn) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
D451N (p.Asp451Asn) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.49 / 1. The record also includes population frequency data, published literature, and structural context.
D451N (p.Asp451Asn) variant details
- p.Asp451Asn
- rs1331303188
- gnomAD 6-111567626-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.49
- REVEL 0.27
- CADD 27.10
- PolyPhen-2 0.84
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available