D441Y (p.Asp441Tyr) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
D441Y (p.Asp441Tyr) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
D441Y (p.Asp441Tyr) variant details
- p.Asp441Tyr
- gnomAD 6-111567689-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.695
- REVEL 0.61
- CADD 28.20
- PolyPhen-2 0.97
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available