D441V (p.Asp441Val) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
D441V (p.Asp441Val) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data, published literature, and structural context.
D441V (p.Asp441Val) variant details
- p.Asp441Val
- gnomAD 6-111567688-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.701
- REVEL 0.73
- CADD 28.30
- PolyPhen-2 0.91
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available