A126E (p.Ala126Glu) variant of TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2)
A126E (p.Ala126Glu) in TRAF3IP2 (E3 ubiquitin ligase TRAF3IP2) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as likely benign in the context of not specified. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes structural context.
A126E (p.Ala126Glu) variant details
- p.Ala126Glu
- rs893763256
- ClinGen CA365368724
- ClinVar RCV004315786
- Likely benign
- not specified
- Missense
- Variant Prioritization Score for Impact Estimate 0.287
- AlphaMissense 0.07
- MetaLR 0.01
- MetaSVM -0.95
- PolyPhen-2 0.02
- SIFT 0.08
- MutPred 0.13
- ClinVar: Likely benign (not specified)
- EBI: Likely benign
- UniProt: Likely benign
- Structural context available