T66S (p.Thr66Ser) variant of TRAF3 (TNF receptor-associated factor 3)
T66S (p.Thr66Ser) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data, published literature, and structural context.
T66S (p.Thr66Ser) variant details
- p.Thr66Ser
- gnomAD 14-102870397-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.588
- REVEL 0.63
- CADD 25.00
- PolyPhen-2 0.89
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available