T23I (p.Thr23Ile) variant of TRAF3 (TNF receptor-associated factor 3)
T23I (p.Thr23Ile) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
T23I (p.Thr23Ile) variant details
- p.Thr23Ile
- ExAC rs774134145
- gnomAD rs774134145
- Missense
- Variant Prioritization Score for Impact Estimate 0.284
- REVEL 0.04
- MetaLR 0.06
- MetaSVM -1.05
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 0.05
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available