S62I (p.Ser62Ile) variant of TRAF3 (TNF receptor-associated factor 3)
S62I (p.Ser62Ile) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
S62I (p.Ser62Ile) variant details
- p.Ser62Ile
- gnomAD 14-102870386-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.20
- CADD 19.20
- PolyPhen-2 0.03
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available