S62C (p.Ser62Cys) variant of TRAF3 (TNF receptor-associated factor 3)
S62C (p.Ser62Cys) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
S62C (p.Ser62Cys) variant details
- p.Ser62Cys
- gnomAD 14-102870385-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.29
- CADD 23.60
- PolyPhen-2 0.33
- SIFT 0.00
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available