S4R (p.Ser4Arg) variant of TRAF3 (TNF receptor-associated factor 3)
S4R (p.Ser4Arg) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
S4R (p.Ser4Arg) variant details
- p.Ser4Arg
- TOPMed rs1292487225
- Missense
- Variant Prioritization Score for Impact Estimate 0.279
- REVEL 0.21
- MetaLR 0.07
- MetaSVM -1.04
- CADD 18.30
- PolyPhen-2 0.26
- SIFT 0.06
- Population evidence available
- Structural context available