Q14P (p.Gln14Pro) variant of TRAF3 (TNF receptor-associated factor 3)
Q14P (p.Gln14Pro) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
Q14P (p.Gln14Pro) variant details
- p.Gln14Pro
- cosmic curated COSV61025
- TOPMed rs896716603
- gnomAD rs896716603
- Missense
- Variant Prioritization Score for Impact Estimate 0.167
- REVEL 0.06
- MetaLR 0.09
- MetaSVM -1.13
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Structural context available