P34L (p.Pro34Leu) variant of TRAF3 (TNF receptor-associated factor 3)
P34L (p.Pro34Leu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
P34L (p.Pro34Leu) variant details
- p.Pro34Leu
- gnomAD 14-102870302-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- REVEL 0.23
- CADD 25.40
- PolyPhen-2 0.94
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available
- Literature evidence available