N16T (p.Asn16Thr) variant of TRAF3 (TNF receptor-associated factor 3)
N16T (p.Asn16Thr) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
N16T (p.Asn16Thr) variant details
- p.Asn16Thr
- cosmic curated COSV61023
- ExAC rs780863420
- gnomAD rs780863420
- Missense
- Variant Prioritization Score for Impact Estimate 0.209
- REVEL 0.08
- MetaLR 0.05
- MetaSVM -1.01
- CADD 14.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.013)
- Structural context available