L21Q (p.Leu21Gln) variant of TRAF3 (TNF receptor-associated factor 3)
L21Q (p.Leu21Gln) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L21Q (p.Leu21Gln) variant details
- p.Leu21Gln
- gnomAD 14-102870263-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- REVEL 0.08
- CADD 16.50
- PolyPhen-2 0.01
- SIFT 0.09
- Population evidence available
- Structural context available
- Literature evidence available