L13Q (p.Leu13Gln) variant of TRAF3 (TNF receptor-associated factor 3)
L13Q (p.Leu13Gln) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
L13Q (p.Leu13Gln) variant details
- p.Leu13Gln
- gnomAD 14-102870239-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.03
- CADD 20.70
- PolyPhen-2 0.09
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 1.8e-05)
- Structural context available
- Literature evidence available