K6R (p.Lys6Arg) variant of TRAF3 (TNF receptor-associated factor 3)
K6R (p.Lys6Arg) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
K6R (p.Lys6Arg) variant details
- p.Lys6Arg
- TOPMed rs937992126
- gnomAD rs937992126
- Missense
- Variant Prioritization Score for Impact Estimate 0.277
- REVEL 0.12
- MetaLR 0.11
- MetaSVM -0.81
- CADD 22.60
- PolyPhen-2 0.24
- SIFT 0.57
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available