K6N (p.Lys6Asn) variant of TRAF3 (TNF receptor-associated factor 3)
K6N (p.Lys6Asn) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
K6N (p.Lys6Asn) variant details
- p.Lys6Asn
- TOPMed rs1281040764
- gnomAD rs1281040764
- Missense
- Variant Prioritization Score for Impact Estimate 0.182
- REVEL 0.03
- MetaLR 0.05
- MetaSVM -1.01
- CADD 20.80
- PolyPhen-2 0.01
- SIFT 0.34
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available