K5R (p.Lys5Arg) variant of TRAF3 (TNF receptor-associated factor 3)
K5R (p.Lys5Arg) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
K5R (p.Lys5Arg) variant details
- p.Lys5Arg
- ExAC rs755457663
- gnomAD rs755457663
- Missense
- Variant Prioritization Score for Impact Estimate 0.332
- REVEL 0.19
- MetaLR 0.06
- MetaSVM -1.04
- CADD 20.50
- PolyPhen-2 0.01
- SIFT 0.67
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available