K5E (p.Lys5Glu) variant of TRAF3 (TNF receptor-associated factor 3)
K5E (p.Lys5Glu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
K5E (p.Lys5Glu) variant details
- p.Lys5Glu
- TOPMed rs1335113299
- gnomAD rs1335113299
- Missense
- Variant Prioritization Score for Impact Estimate 0.271
- REVEL 0.17
- MetaLR 0.11
- MetaSVM -1.01
- CADD 20.30
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available