K55E (p.Lys55Glu) variant of TRAF3 (TNF receptor-associated factor 3)
K55E (p.Lys55Glu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
K55E (p.Lys55Glu) variant details
- p.Lys55Glu
- gnomAD 14-102870364-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.22
- CADD 22.50
- PolyPhen-2 0.19
- SIFT 0.28
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available