K45E (p.Lys45Glu) variant of TRAF3 (TNF receptor-associated factor 3)
K45E (p.Lys45Glu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
K45E (p.Lys45Glu) variant details
- p.Lys45Glu
- gnomAD 14-102870334-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.343
- REVEL 0.25
- CADD 18.90
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available