K40R (p.Lys40Arg) variant of TRAF3 (TNF receptor-associated factor 3)
K40R (p.Lys40Arg) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
K40R (p.Lys40Arg) variant details
- p.Lys40Arg
- gnomAD 14-102870320-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.195
- REVEL 0.06
- CADD 19.20
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available