H57Y (p.His57Tyr) variant of TRAF3 (TNF receptor-associated factor 3)
H57Y (p.His57Tyr) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
H57Y (p.His57Tyr) variant details
- p.His57Tyr
- ExAC rs749156219
- TOPMed rs749156219
- gnomAD rs749156219
- Missense
- Variant Prioritization Score for Impact Estimate 0.355
- REVEL 0.17
- MetaLR 0.26
- MetaSVM -0.72
- CADD 22.50
- PolyPhen-2 0.00
- SIFT 0.39
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available