H22Y (p.His22Tyr) variant of TRAF3 (TNF receptor-associated factor 3)
H22Y (p.His22Tyr) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
H22Y (p.His22Tyr) variant details
- p.His22Tyr
- gnomAD 14-102870265-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.23
- REVEL 0.05
- CADD 13.40
- PolyPhen-2 0.01
- SIFT 0.11
- Population evidence available
- Structural context available
- Literature evidence available