G37E (p.Gly37Glu) variant of TRAF3 (TNF receptor-associated factor 3)
G37E (p.Gly37Glu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data and structural context.
G37E (p.Gly37Glu) variant details
- p.Gly37Glu
- ExAC rs758854542
- gnomAD rs758854542
- Missense
- Variant Prioritization Score for Impact Estimate 0.446
- REVEL 0.28
- MetaLR 0.14
- MetaSVM -0.99
- CADD 24.60
- PolyPhen-2 0.85
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available