G28E (p.Gly28Glu) variant of TRAF3 (TNF receptor-associated factor 3)
G28E (p.Gly28Glu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
G28E (p.Gly28Glu) variant details
- p.Gly28Glu
- gnomAD rs1288284677
- Missense
- Variant Prioritization Score for Impact Estimate 0.173
- REVEL 0.01
- MetaLR 0.06
- MetaSVM -0.99
- CADD 15.90
- PolyPhen-2 0.01
- SIFT 0.19
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available