G11S (p.Gly11Ser) variant of TRAF3 (TNF receptor-associated factor 3)
G11S (p.Gly11Ser) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
G11S (p.Gly11Ser) variant details
- p.Gly11Ser
- gnomAD rs1203054993
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.07
- MetaLR 0.05
- MetaSVM -1.02
- CADD 4.62
- PolyPhen-2 0.00
- SIFT 0.70
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available