E54G (p.Glu54Gly) variant of TRAF3 (TNF receptor-associated factor 3)
E54G (p.Glu54Gly) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.45 / 1. The record also includes population frequency data, published literature, and structural context.
E54G (p.Glu54Gly) variant details
- p.Glu54Gly
- gnomAD 14-102870362-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.451
- REVEL 0.35
- CADD 23.20
- PolyPhen-2 0.01
- SIFT 0.11
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available