E2D (p.Glu2Asp) variant of TRAF3 (TNF receptor-associated factor 3)
E2D (p.Glu2Asp) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data.
E2D (p.Glu2Asp) variant details
- p.Glu2Asp
- gnomAD rs1435980220
- Missense
- Variant Prioritization Score for Impact Estimate 0.189
- REVEL 0.06
- MetaLR 0.04
- MetaSVM -1.03
- CADD 16.70
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 2.7e-06)