D8V (p.Asp8Val) variant of TRAF3 (TNF receptor-associated factor 3)
D8V (p.Asp8Val) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
D8V (p.Asp8Val) variant details
- p.Asp8Val
- ExAC rs779404357
- gnomAD rs779404357
- Missense
- Variant Prioritization Score for Impact Estimate 0.346
- REVEL 0.27
- MetaLR 0.11
- MetaSVM -1.10
- CADD 23.10
- PolyPhen-2 0.09
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 6.3e-06)
- Structural context available