D8N (p.Asp8Asn) variant of TRAF3 (TNF receptor-associated factor 3)
D8N (p.Asp8Asn) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
D8N (p.Asp8Asn) variant details
- p.Asp8Asn
- gnomAD 14-102870223-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.414
- REVEL 0.19
- CADD 22.10
- PolyPhen-2 0.03
- SIFT 0.43
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available