D8G (p.Asp8Gly) variant of TRAF3 (TNF receptor-associated factor 3)
D8G (p.Asp8Gly) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
D8G (p.Asp8Gly) variant details
- p.Asp8Gly
- ExAC rs779404357
- gnomAD rs779404357
- Missense
- Variant Prioritization Score for Impact Estimate 0.269
- REVEL 0.12
- MetaLR 0.08
- MetaSVM -1.07
- CADD 22.20
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available