D8E (p.Asp8Glu) variant of TRAF3 (TNF receptor-associated factor 3)
D8E (p.Asp8Glu) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
D8E (p.Asp8Glu) variant details
- p.Asp8Glu
- TOPMed rs1218851959
- gnomAD rs1218851959
- Missense
- Variant Prioritization Score for Impact Estimate 0.103
- REVEL 0.08
- MetaLR 0.06
- MetaSVM -1.03
- CADD 0.72
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available