D8A (p.Asp8Ala) variant of TRAF3 (TNF receptor-associated factor 3)
D8A (p.Asp8Ala) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
D8A (p.Asp8Ala) variant details
- p.Asp8Ala
- ExAC rs779404357
- gnomAD rs779404357
- Missense
- Variant Prioritization Score for Impact Estimate 0.296
- REVEL 0.18
- MetaLR 0.08
- MetaSVM -1.06
- CADD 21.80
- PolyPhen-2 0.02
- SIFT 0.20
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available