C76G (p.Cys76Gly) variant of TRAF3 (TNF receptor-associated factor 3)
C76G (p.Cys76Gly) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.77 / 1. The record also includes population frequency data, published literature, and structural context.
C76G (p.Cys76Gly) variant details
- p.Cys76Gly
- gnomAD 14-102870427-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.767
- REVEL 0.86
- CADD 27.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available