C68R (p.Cys68Arg) variant of TRAF3 (TNF receptor-associated factor 3)
C68R (p.Cys68Arg) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.81 / 1. The record also includes population frequency data, published literature, and structural context.
C68R (p.Cys68Arg) variant details
- p.Cys68Arg
- gnomAD 14-102870403-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.814
- REVEL 0.93
- CADD 27.70
- PolyPhen-2 0.98
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available