C61G (p.Cys61Gly) variant of TRAF3 (TNF receptor-associated factor 3)
C61G (p.Cys61Gly) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
C61G (p.Cys61Gly) variant details
- p.Cys61Gly
- gnomAD rs1385981615
- Missense
- Variant Prioritization Score for Impact Estimate 0.564
- REVEL 0.58
- MetaLR 0.39
- MetaSVM -0.21
- CADD 24.10
- PolyPhen-2 0.60
- SIFT 0.71
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available