C56F (p.Cys56Phe) variant of TRAF3 (TNF receptor-associated factor 3)
C56F (p.Cys56Phe) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.89 / 1. The record also includes population frequency data, published literature, and structural context.
C56F (p.Cys56Phe) variant details
- p.Cys56Phe
- gnomAD 14-102870368-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.891
- REVEL 0.96
- CADD 28.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available