C53W (p.Cys53Trp) variant of TRAF3 (TNF receptor-associated factor 3)
C53W (p.Cys53Trp) in TRAF3 (TNF receptor-associated factor 3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.61 / 1. The record also includes population frequency data, published literature, and structural context.
C53W (p.Cys53Trp) variant details
- p.Cys53Trp
- gnomAD 14-102870360-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.615
- REVEL 0.89
- CADD 22.50
- PolyPhen-2 1.00
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available