S69T (p.Ser69Thr) variant of TPO (Thyroid peroxidase)
S69T (p.Ser69Thr) in TPO (Thyroid peroxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and published literature.
S69T (p.Ser69Thr) variant details
- p.Ser69Thr
- gnomAD 3-184375540-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.55
- CADD 23.90
- PolyPhen-2 0.96
- SIFT 0.05
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Literature evidence available