S69I (p.Ser69Ile) variant of TPO (Thyroid peroxidase)
S69I (p.Ser69Ile) in TPO (Thyroid peroxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.55 / 1. The record also includes population frequency data and published literature.
S69I (p.Ser69Ile) variant details
- p.Ser69Ile
- rs141465516
- gnomAD 3-184375540-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.554
- CADD 24.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 4.8e-05)
- Literature evidence available