S69G (p.Ser69Gly) variant of TPO (Thyroid peroxidase)
S69G (p.Ser69Gly) in TPO (Thyroid peroxidase) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data and published literature.
S69G (p.Ser69Gly) variant details
- p.Ser69Gly
- gnomAD 3-184375541-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.64
- CADD 25.70
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Literature evidence available